I have been on the depo for almost two years. I was due two weeks ago for my shot and decided not to get it because I have gained 25 pounds and have not had a period since I started it (which I don't mind). I am experiencing headaches, irritability, fatigue, extreme hot flashes and severe dizziness. I am going to have to quit my bartending job because I get so dizzy and fear I'm going to pass out and hurt myself. I'm 23 and all the accounts of hot flashes I have read about say that it is from premenopaus but clearly I'm not about to start menopause. How long do these adverse side effects last? Will I loose the weight I gained? I'm reading mixed responses.