Medicos from the Los Angeles Biomedical Research Institute say a progestogen-only treatment halted bleeding in women suffering from extremely heavy periods.
In the pilot study, the patients received a 150-milligram injection of Depomedroxyprogesterone acetate (DMPA) and then were given medroxyprogesterone acetate (MPA) 20 milligram pills that were to be taken orally every eight hours for three days.
Within five days of receiving the therapy, bleeding had ceased in 44 of the 48 women in the study, and the other four were only experiencing spotting. The mean time to bleeding cessation was 2.6 days, leading the researchers to conclude the progestogen-only treatment was an effective therapy for acute abnormal uterine bleeding.
"Excessive uterine bleeding is a common problem we see in gynecological practices and emergency rooms. It can interfere with women's daily activities and put them at risk for anemia," said lead researcher Anita L. Nelson. "Until now, there has been no [FDA] approved products for short-term treatment of this condition."
She also said the treatment had "good compliance, few side effects and high patient satisfaction." In addition, she said it was an attractive treatment option for women with contraindications to estrogen, those who need more prolonged therapy and those who may have difficulty with daily pill administration. The study appears in the American Journal of Obstetrics and Gynecology.
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Source: Los Angeles Biomedical Research Institute