Women's health discussion
forums, research news and
women's health issues.
DISCUSSION FORUMS...

Trying To Conceive

Surviving Miscarriage

Overcoming Infertility

Reproductive Health

General Health

Contraception

Pregnancy

Parenting

Babies and Toddlers

Relationships

Mental Health

Diet & Weight


ARTICLES ABOUT...

Relationships

Sexual Dysfunction

Looking Good

STDs

Men

Contraception

Reproductive Health

Conceiving

Pregnancy

Incontinence

Mental Health

Children's Health

Eating Well

Healthy Living

Supplements

Menopause

Weight Issues

Breast Cancer

Custom Search

26 March 2007
Estriol Could Emerge As MS Treatment

What is it about pregnancy that eases the symptoms of MS? While Canadian researchers think the answer might be the hormone prolactin, researchers from UCLA think the answer might be another sex hormone - estriol. To investigate it's effects further, they are just about to start a two-year trial involving 150 women.

The new investigation follows on from a pilot study in which 10 non-pregnant women with MS were given estriol, yielding what researcher Rhonda Voskuhl described as "pretty remarkable" results - an 80 percent drop in inflammatory lesions in the brain, a hallmark of the disease.

Estriol is a hormone produced by the placenta during pregnancy. It is thought that its role is to suppress a woman's immune system when she is pregnant, so that the fetus will not be seen by the body as a foreign "invader". "The beauty of estriol is that it can be given as a pill and also that it's not a new drug; it has decades of safety behind it," said Voskuhl. Estriol has been in widespread use outside the US as a hormone replacement therapy for women with menopausal symptoms. The fact that the pill already exists, says Voskuhl, should dramatically reduce the cost of treatment.

Viskuhl believes that the drug potentially provides a one-two punch against MS, both reducing the ability of immune cells to attack the brain, as well as making the brain more resistant to damage if any immune cells do make it through. "It's a two-pronged approach an anti-inflammatory prong to reduce the attacks, but also a neuroprotective prong to make the brain suffer less damage in case of an attack," she noted.

Related articles:
Pregnancy Hormone Key To MS?
Stress May Trigger Multiple Sclerosis

Source: University of California, Los Angeles (UCLA), Health Sciences


Discussion Forums     About Us     Privacy
Your use of this website indicates your agreement to our terms of use.
2002 - 2013 Aphrodite Women's Health and its licensors. All rights reserved.